Based on a true story, this tale of madness and power is elegantly and humorously told with wit and superb acting. King George likely suffered from porphyria, a rare, inherited blood disorder whose hallmark symptom is blue urine. The historical account of 18th century medical care and knowledge is fascinating and frightening. Nigel Hawthorne plays the mad royal with Helen Mirren as Queen Charlotte.

After the film, Dr. Michael McVaugh will lead a brief discussion about the science and ethics involved in the movie.