The Hemminger group is broadly interested in how large sets of information can be organized, analyzed, retrieved and displayed. Most of the databases they use and develop are relevant to medical and genomic applications, but the input information can take a variety of forms such as DNA sequences, proteins, images, research articles, and experimental data. Specific areas of interest are described below:

Bioinformatics: Development of a novel notational system for representing biological systems information and knowledge. Development of standards for the representation and exchange of proteomics experimental results.

Medical Informatics: Standardization of medical imaging and reporting using the Digital Imaging and Communications (DICOM) standards.

Digital Libraries: Development of a digital archive called “NeoRef” for any original material including articles, research notes, theses, books, genetic sequences, and concepts. All of these materials can be stored, searched and retrieved conveniently without the need for the traditional framework of publishers and review systems. Creation of the Center for Research and Development of Digital Libraries (CRADLE), and initiation of university support for archiving and publishing electronic theses, dissertations and journal articles at UNC.

Databases: Integrating and searching large, disparate databases. Primary emphasis is on biological databases such as genetics, protoemics and metabolomics.

Datamining:
Knowledge discovery via datamining of large, integrated databases. Application of statistical pattern recognition and feature analysis techniques to genomic and proteomic databases.

User Interface Design: Development and design of computer human interaction interfaces for practitioners in science and medicine.

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Selected Publications:
Hemminger BM, Saelim B, Sullivan PF. (2006) TAMAL: an integrated approach to choosing SNPs for genetic studies of human complex traits. Bioinformatics. 22:626-7.

Hemminger BM, Molina PL, Egan TM, Detterbeck FC, Muller KE, Coffey CS, Lee JK. (2005) Assessment of real-time 3D visualization for cardiothoracic diagnostic evaluation and surgery planning. J Digit Imaging 18:145-53.

Hemminger BM. (2003) Soft copy display requirements for digital mammography. J Digit Imaging 16:292-305.

DICOM 3.0 (2003) International Standard. [website]

Hemminger BM. (2003) Scholarly Communcations in an Electronic Age. ASIST panel presentation, San Diego, CA. [powerpoint presentation]

Hemminger BM. (2002) Softcopy Display for Digital Mammography. Proc SPIE Medical Imaging: Visualization, Image-Guided Procedures, and Display vol 4681-73.


 

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